Modify Therapy/Monitor Closely. The name of your medicine is Cyklokapron 500 mg film-coated tablets, which will be called Cyklokapron tablets throughout this leaflet. norethindrone (contraceptive), tranexamic acid lorazepam, tranexamic acid If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. Tranexamic acid (Cyklokapron) is a medication used short term to prevent people with hemophilia from bleeding too much while getting a tooth pulled (tooth extraction). + periodically; ophthalmic exam at baseline, then if tx >3mo cont. Tranexamic acid may also be used for purposes not listed in this medication guide. com.epocrates.rxweb.beans.StringCollection@3dedf6b4, estrogens, conjugated (hormone replacement), estrogens, esterified (hormone replacement), hydroxyprogesterone (hormone replacement), medroxyprogesterone (hormone replacement), norethindrone acetate (hormone replacement), progesterone vaginal (hormone replacement), antihemophilic factor (factor VIII)/von Willebrand factor complex, com.epocrates.rxweb.beans.StringCollection@6af13a2c, com.epocrates.rxweb.beans.StringCollection@58733cd1, com.epocrates.rxweb.beans.DrugOtherInfoBean@6cb58488, com.epocrates.rxweb.beans.DrugOtherInfoBean@774f1883, acetaminophen/chlorpheniramine/dextromethorphan, acetaminophen/chlorpheniramine/dextromethorphan/phenylephrine, acetaminophen/chlorpheniramine/dextromethorphan/pseudoephedrine, acetaminophen/chlorpheniramine/phenylephrine, acetaminophen/dextromethorphan/phenylephrine, acetaminophen/dextromethorphan/phenylephrine/guaifenesin, acetaminophen/dextromethorphan/pseudoephedrine, acetaminophen/diphenhydramine/dextromethorphan, acetaminophen/diphenhydramine/phenylephrine, acetaminophen/doxylamine/dextromethorphan, acetaminophen/doxylamine/dextromethorphan/phenylephrine, acetaminophen/triprolidine/dextromethorphan, acetaminophen/triprolidine/dextromethorphan/phenylephrine, aclidinium bromide/formoterol fumarate inhaled, adenovirus type 4 and type 7 vaccine, live oral, Adenovirus Type 4 and Type 7 Vaccine, Live Oral, Advil Dual Action with Acetaminophen Back Pain, Alka-Seltzer Extra Strength Heartburn Relief Gum, Alka-Seltzer Extra Strength Heartburn ReliefChews, Alka-Seltzer Plus Maximum Strength Cold & Cough, Alka-Seltzer Plus Maximum Strength Cold & Cough PowerMax, Alka-Seltzer Plus Maximum Strength Cold & Flu Day, Alka-Seltzer Plus Maximum Strength Cold & Flu Day PowerMax, Alka-Seltzer Plus Maximum Strength Cold & Flu Night, Alka-Seltzer Plus Maximum Strength Cold & Flu Night PowerMax, Alka-Seltzer Plus Maximum Strength Cough & Mucus DM. + These products are provided 'AS IS' and 'as available' for use, without warranties of any kind, either express or implied. Cyklokapron, an alternative treatment should be considered. tranexamic acid injection, anti-inhibitor coagulant complex. + dexamethasone, avoid combo: combo may incr. tiagabine, tranexamic acid This drug is available at a higher level co-pay. antihemophilic factor (factor VIII, human)/von Willebrand factor ... antihemophilic factor (factor VIII, recombinant). Stop using Cyklokapron and call your doctor at once if you have: problems with your vision (including color vision); a light-headed feeling, like you might pass out; painful or difficult urination, blood in your urine; signs of a stroke--sudden numbness or weakness (especially on one side of the body), severe headache, slurred speech, balance problems; signs of a blood clot in the lung--chest pain, sudden cough, wheezing, rapid breathing, coughing up blood; or. medroxyprogesterone (contraceptive), tranexamic acid Humate-P Alternatives Compared Humate-P (antihemophilic factor/von willebrand factor) Desmopressin DDAVP (desmopressin) Prescription only Prescribed for Hemophilia A, von Willebrand Disease. What are some common side effects of tranexamic acid (Cyklokapron)? + lenalidomide, tranexamic acid This list is not complete. Do not take more than 3 doses (6 tablets) in 24 hours. + Due to the powerful impact on the organism, Cyklokapron is frequently used to warn bleeding, especially in patients, who are diagnosed with hemophilia. Advise patients to use an effective alternative (nonhormonal) contraceptive method [see Warnings and Precautions (5.1), Drug Interactions (7.1)]. polyethylene glycol, caution advised, especially if polyethylene glycol bowel prep use and high-dose IV tranexamic acid: combo may incr. It will look at the number of HAE attacks and how donidalorsen affects quality of life. The product information provided by this site is intended only for health care professionals, patients, consumers and caregivers in the United States. Latest News Are you looking for information on tranexamic acid (Lysteda) instead? Stop taking tranexamic acid and see your doctor right away if you have any eye problems or change in vision.Tell your doctor if there is a change in your bleeding pattern or heavy bleeding lasts or gets worse. Alka-Seltzer Plus Maximum Strength Severe Sinus, Allergy & Cough ... Alka-Seltzer Plus Maximum Strength Sinus & Cold PowerMax, Alka-Seltzer Plus Maximum Strength Sinus & Cold PowerMax Night. And medical organizations like the International Federation of Gynecology and Obstetrics (FIGO) and the World Health Organization (WHO) recommend the use of tranexamic acid (Cyklokapron) (along with other standard practices) in females with excessive bleeding after vaginal birth or cesarean section (C-section). norgestimate (hormone replacement), tranexamic acid University of Iowa College of Dentistry and Dental Clinics. + The recipient will receive more details and instructions to access this offer. lamotrigine, tranexamic acid Reduced menstrual blood loss. desogestrel (contraceptive), contraindicated: combo may incr. Consult your doctor before breast-feeding. Consult your pharmacist or local waste disposal company. commonly, these are "non-preferred" brand drugs. cenobamate, tranexamic acid Cyklokapron Tablet Cyklokapron Tablet - Uses, Side Effects, and More Generic Name (S): tranexamic acid View Free Coupon Uses This medication is used short-term in people with a certain type. anti-inhibitor coagulant complex, avoid combo w/in 6-12h of anti-inhibitor coagulant complex use: combo may incr. To report an adverse event related to Pfizer-BioNTech COVID-19 Vaccine (also known as COMIRNATY®, COVID-19 mRNA, Vaccine BNT162b2 or BNT162) or Pfizer COVID-19 Treatment (also known as PAXLOVID™ (nirmatrelvir tablets; ritonavir tablets)), and you are not part of a clinical trial* for this product, click the link below to submit your information: *If you are involved in a clinical trial for either product, adverse events should be reported to your coordinating study site. This medication is usually given just before the dental procedure, and daily for up to 8 days afterward. Exclusivity is the sole marketing rights granted by the FDA to a manufacturer upon the approval of a drug and may run simultaneously with a patent. Last updated on Feb 1, 2022. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. 34 active trials are in progress to assess the potential of Cyklokapron in managing Hemophilia, Hemorrhage and Hereditary Angioedemas. Uses, Side Effects, & Dosage, What is Implanon? pomalidomide, tranexamic acid Possible side effects 5. Monitor Closely (1)tranexamic acid injection decreases effects of defibrotide by pharmacodynamic antagonism. ponatinib, tranexamic acid CYKLOKAPRON has to be used in these patients, advise them to use an effective alternative (nonhormonal) contraceptive method. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. + If you have any questions regarding the information, consult your doctor or pharmacist.Take this medication by mouth with or without food as directed by your doctor, usually 2 tablets 3 times a day (morning, afternoon, bedtime). + risk of seizures (additive effects), tranexamic acid Learn more at GoodRx. + asparaginase, tranexamic acid This trialwill compare the effectiveness of different treatments for restoring the gum and bone around immediate implants, which are used to replace missing teeth. Drugs A to Z Cyklokapron Print Save Cyklokapron Generic name: tranexamic acid (Cyklokapron) [ tran-ex-AM-ik-AS-id ] Drug class: Miscellaneous coagulation modifiers Medically reviewed by Drugs.com on Oct 19, 2022. Inform patients that CYKLOKAPRON may cause seizures and to contact their healthcare provider for any signs or symptoms suggestive of seizures [see Warnings and Precautions (5.3)]. norethindrone acetate (hormone replacement), tranexamic acid Each vial or ampule is for one use only. For heavy periods, it is usually taken for four days, or for seven days to treat other types of bleeding that does not stop on its own." Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. nintedanib, tranexamic acid Modify Therapy/Monitor Closely. Risk of thrombosis. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Overdose symptoms may include headache, confusion, vision problems, vomiting, diarrhea, numbness or weakness, problems with speech or balance, feeling light-headed, or fainting. + Avoid or Use Alternate Drug. + Cyklokapron 100mg Injection is an anti-fibrinolytic. Risk of thrombosis. Uses, Side Effects, & Dosage, What is Lysteda? + http://www.goodrx.com/cyklokapron. Use the medicine exactly as directed. + numbness of the hands. drospirenone (hormone replacement), tranexamic acid estradiol (contraceptive), tranexamic acid Coadministration increases risk of thrombosis. Side-effects are usually minor and rare." coagulation factor IX, tranexamic acid calaspargase, tranexamic acid Take your next dose at the regular time. Patients and physicians can contact RxPathways at (866) 706-2400 or visit the website for more information on these programs www.pfizerrxpathways.com. Therapeutic effects Decreased bleeding following dental surgery in hemophiliacs. Advise patients using hormonal contraception that combined use with CYKLOKAPRON may increase the risk for thromboembolic adverse reactions and to use effective alternative (nonhormonal) contraception during therapy with CYKLOKAPRON [see Warnings and Precautions (5.1), Drug Interactions (7.1), Use in Specific Populations (8.3)]. A drug company seeking approval to market a generic equivalent must refer to the Reference Listed Drug in its Abbreviated New Drug Application (ANDA). Tranexamic acid may increase the thrombogenic activities of Andexanet alfa. + factor IX complex (Bebulin, Bebulin VH, Profilnine, and others). Advise patients using hormonal contraception that combined use with CYKLOKAPRON may increase the risk for thromboembolic adverse reactions and to use effective alternative (nonhormonal) contraception during therapy with CYKLOKAPRON [see Warnings and Precautions (5.1), Drug Interactions (7.1), Use in Specific Populations (8.3)]. MISSED DOSE: If you miss a dose, take it as soon as you remember. These medications may be counterfeit and potentially unsafe. Hemostasis: Fibrinolysis Inhibitors, Mechanism of Actioncompetitively inhibits multiple plasminogen binding sites, decreasing plasmin formation and fibrinolysis, DEA/FDA: Rx (Requires prescription; not a controlled substance), from puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue. Contraindicated (1)tranexamic acid injection increases effects of prothrombin complex concentrate, human by pharmacodynamic synergism. Concomitant use of CYKLOKAPRON, which is an antifibrinolytic, with hormonal contraceptives may increase the risk for thromboembolic adverse reactions. Cyklokapron is a prescription medicine used to prevent bleeding in relation to Dental Extraction in Patients with Hemophilia. tranexamic acid injection decreases effects of defibrotide by pharmacodynamic antagonism. - Anonymous Online Contributor, "The medicine will not have its full effect for up to 24 hours. risk of thrombosis (additive effects), tranexamic acid Avoid or Use Alternate Drug. It is being done in a small group of people and is double-blind, meaning that neither the participants nor the researchers know who is receiving the drug or the placebo. Coadministration ma. SCr 1.36-2.83 mg/dL (120-250 micromoles/L): 10 mg/kg IV q12hr OR 15 mg/kg PO q12hr, SCr 2.83-5.66 mg/dL (250-500 micromoles/L): 10 mg/kg IV qDay OR 15 mg/kg PO qDay, SCr >5.66 mg/dL (>500 micromoles/L): 10 mg/kg IV q48hr OR 15 mg/kg PO q48hr; alternatively, 5 mg/kg IV qDay OR 7.5 mg/kg PO qDay, Visual defects (color vision change or visual loss) reported, In addition, although not seen in humans, focal areas of retinal degeneration have been observed in cats and dogs following oral or intravenous tranexamic acid at doses between 250 to 1600 mg/kg/day (1.6 to 22 times recommended usual human dose based on body surface area) from 6 days to 1 year, No retinal changes observed in eye examinations of patients treated with tranexamic acid for up to 8 years; patients expected to be treated for greater than 3 months may consider ophthalmic monitoring including visual acuity and optical coherence tomography at regular intervals; discontinue tranexamic acid in sodium chloride injection if changes in ophthalmological examination occur, May cause seizures, including focal and generalized seizures; the most common setting for tranexamic acid-induced seizures has been during cardiovascular surgery (a setting in which drug is not FDA approved and which uses doses of up to ten-fold higher than recommended human dose and in patients inadvertently given tranexamic acid into the neuraxial system), Consider dose reduction during surgery and dose adjustments for patients with clinical conditions such as renal dysfunction; closely monitor patient during surgery, Consider electroencephalogram (EEG) monitoring for patients with history of seizures or who experience myoclonic movements, twitching, or show evidence of focal seizures; discontinue drug if seizures occur, Reproduction studies performed in mice, rats, and rabbits have not revealed any adverse effects on fetus due to tranexamic acid administered during organogenesis; doses examined were multiples of up to 3 times (mouse), 6 times (rat), and 3 times (rabbit) maximum human dose based on body surface area in the mouse, rat, and rabbit, respectively, Concomitant use of drug, which is an antifibrinolytic, with hormonal contraceptives may increase risk for thromboembolic adverse reactions; advise patients to use an effective alternative (nonhormonal) contraceptive method. + The following products are equivalent to Cyklokapron: tranexamic acid injectable;injection Manufacturer: ACIC PHARMS Approval date: February 11, 2014 Strength (s): 100MG/ML [ AP] Manufacturer: AKORN Approval date: November 17, 2011 Strength (s): 100MG/ML [ AP] Manufacturer: AM REGENT Approval date: August 10, 2011 Strength (s): 100MG/ML [ AP] Humate-P may also be used for purposes not listed in this medication guide. Serious - Use Alternative (3) anti-inhibitor coagulant complex. A UK MHRA approved Generic Manufacturer. Prescription only Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. You should not use Cyklokapron if you are allergic to tranexamic acid, or if you have: problems with the blood vessels in your eyes; a history of stroke, blood clot, or bleeding in your brain. Contraindicated. Tranexamic acid (Cyklokapron) can also cause seizures and vision-related side effects in rare cases. This website also contains material copyrighted by 3rd parties. "Cyklokapron is a man-made form of lysine, an amino acid, used to prevent bleeding in people with hemophilia who need dental procedures. The patent assigns exclusive legal right to the inventor or patent holder, and may include entities such as the drug brand name, trademark, product dosage form, ingredient formulation, or manufacturing process A patent usually expires 20 years from the date of filing, but can be variable based on many factors, including development of new formulations of the original chemical, and patent infringement litigation. pazopanib, tranexamic acid Tranexamic acid may increase the thrombogenic activities of Albutrepenonacog alfa. Monitor Closely (1)tranexamic acid injection, mestranol. + Action Inhibits activation of plasminogen, thereby preventing the conversion of plasminogen to plasmin. + signs of a blood clot in your leg--swelling, warmth, or redness in an arm or leg. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. + thalidomide, tranexamic acid Links to sites outside of Pfizer Medical Information are provided as a resource to the viewer. + Drug class: miscellaneous coagulation modifiers. aminocaproic acid, tranexamic acid + It is not a form of birth control and does not protect against sexually transmitted diseases. Contact the applicable plan Tranexamic acid (Cyklokapron) works by preventing the breakdown of certain clotting proteins in order to allow your blood to clot. methoxy polyethylene glycol-epoetin beta, tranexamic acid Cyklokapron is used to prevent bleeding in people with hemophilia who need to have a tooth pulled. The above information is provided for general + We made a collection of clinical trials featuring Cyklokapron, we think they might fit your search criteria. Alka-Seltzer Plus Maximum Strength Sinus Congestion & Pain PowerF... Alka-Seltzer Plus Severe Cold & Cough PowerFast Fizz, Alka-Seltzer Plus Severe Cold & Flu Night, Alka-Seltzer Plus Severe Cold & Flu PowerFast Fizz, Alka-Seltzer Plus Severe Cold PowerFast Fizz, Alka-Seltzer Plus Severe Cold PowerFast Fizz Night, Alka-Seltzer Plus Severe Cold PowerFast Fizz Non-Drowsy, Alka-Seltzer Plus Severe Sinus, Cold & Cough, aluminum acetate topical (modified Burow's solution), aluminum hydroxide/magnesium hydroxide/simethicone, amyl nitrite/sodium nitrite/sodium thiosulfate, antihemophilic factor (factor VIII, human). + This trial is for hemophilia A or B sufferers to measure how well fitusiran treats bleeding episodes compared to the current standard of care. bazedoxifene, tranexamic acid The amount also deviates as per the mode of delivery (e.g. Create a FREE Epocrates Online account to access full-color images of medications within the drug risk of seizures (additive effects), tranexamic acid In addition, some products evaluated as therapeutically equivalent may have different preservatives or no preservatives at all. and formulary information changes. Uses, Side Effects, & Dosage, What is Amicar? It was first patented in 1957 and approved for use in the United States in 1986. + Contraindicated. Manage and view all your plans together – even plans in different states. Some side effects may occur that usually do not need medical attention. Generic Alternative of Cyklokapron 500mg . If any of these effects last or get worse, tell your doctor or pharmacist promptly.Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Have you considered Cyklokapron clinical trials? Please change your Our medical information is accurate, up to date, and scientifically balanced. Melasma, a condition in which brown patches appear on the face, is a common problem affecting women of color. Inhibits fibrinolysis by displacing plasminogen from fibrin, Reduces plasmin activity, which in turn reduces activation of complement and consumption of C1 esterase inhibitor (C1-NH) and subsequently decreases inflammation associated with hereditary angioedema, Solution: compatible with most common solutions for infusion, Prepare solution same day it will be used, Dilute a single dose w/t 50 mL compatible fluid (eg, NS, Ringers, dextrose/water), 100 mg or fraction thereof over at least 1 min, usually 5 minutes, TRANEXAMIC ACID 650 MILLIGRAM TABLET - ORAL. Individual plans may vary International Federation of Gynecology and Obstetrics (FIGO), Melasma Is Worse for Women of Color: Here’s How to Treat It. immune globulin, tranexamic acid + informational and educational purposes only. Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Most We only share your information with the clinical trials you're trying to access. axitinib, tranexamic acid darbepoetin alfa, tranexamic acid fosphenytoin, tranexamic acid + Tranexamic acid is used to control unwanted bleeding. + + + CYKLOKAPRON solution for injection (100 mg/mL) should be administered by slow intravenous injection. 1 INDICATIONS AND USAGE CYKLOKAPRON® is indicated in patients with hemophilia for short-term use (2 to 8 days) to reduce or prevent hemorrhage and reduce the need for replacement therapy during and following tooth . This drug is available at a higher level co-pay. Contact Pfizer Safety to report an adverse event, side effect or concern about the quality of a Pfizer product: (800) 438-1985, You may also contact the U.S. Food and Drug Administration (FDA) directly to report adverse events or product quality concerns at 1-800-FDA-1088 or www.fda.gov/MedWatch. Copyright(c) 2023 First Databank, Inc. + Truven Health and GoodRx make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Ask your doctor or pharmacist if you don't understand all instructions. estradiol (hormone replacement), tranexamic acid Cyklokapron Alternatives Compared Cyklokapron (tranexamic acid) Tranexamic acid Zoladex (goserelin) Prescription only Prescribed for Bleeding Disorder, Factor IX Deficiency, Hemophilia A. Cyklokapron may also be used for purposes not listed in this medication guide. The use of the Truven Health products is at your sole risk. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. Tranexamic acid may increase the thrombogenic activities of Anti-inhibitor coagulant complex. Do not double the dose to catch up. + This trial is testing how well platelets stored at cold conditions work in cardiac surgery patients who are actively bleeding and need a platelet transfusion.