REPENTANCE - Kidney Bean now has a bigger effect radius, no longer deals damage to the enemies it's charming, and charge time has been reduced to 1 (from 2). Increases the maximum heart limit to 18. Releasing Dark Esau will cause him to charge directly at Jacob and deal damage to anything in his path. See its page for any differences to what is listed here. A blood clot forms through several steps: The blood vessel narrows. Stat Up becomes Stat Down), Any 'Stat down' pills you take give you a permanent +0.6 Damage Up (Horse pills +1.2), Most other pills spawn a black heart when used, including R U A Wizard?, Amnesia, Bad Trip, ?? Holding the fire button charges a spin attack (Damage * 8 + 10). Attributes Curses Upon use, this item summons a ghost near Isaac that will follow him around. At the full 12 charges Isaac does a massive shout, dealing 356 damage to all enemies on the screen, Larynx gains 1 charge every time you take damage (also charges as normal), UNLOCK: Unlock this item by defeating The Beast as Tainted Samson, Recharge time: 12 rooms (Can be used with partial charges), This item gives you a familiar version of The Lost character which dies instantly upon hit, If the familiar survives an entire floor you get one of: 3 soul hearts, 2 eternal hearts or a random item/angel room item, Regenerates at the start of each floor if dead, UNLOCK: Unlock this item by defeating Mother in the Corpse II as The Lost, Bombs now spawn a puddle of red creep upon explosion, dealing 2 damage per tick to enemies touching it, While at 0 bombs, you can also place further bombs now at the cost of 1/2 of a heart (kills The Lost if used like this). Generally every interaction and synergy that applies to Chemical Peel also . During this time he can walk over enemies to mark them for death. Items Has a small chance to take you to the I AM ERROR room, and a smaller chance to teleport to a Black Market, Addicted - Causes you to take a full heart of damage for all sources for the current room. Generally every interaction and synergy that applies to Chemical Peel also applies to Blood Clot. 5c pickups become 3c. While you have this flame you also have that item's effect, The flame deals double your tear damage to any enemies that touch it, but if it takes too much damage the flame will disappear and you lose the item's effect, Wisps are randomly chosen from Item Room, Boss Room and Shop item pools, with a 25% chance to pick the same pool as the current room. item room pool, question mark book, white, When used, spawns 4-8 friendly blue spiders on the floor, REPENTANCE - Used to give 1-4 spiders per use, * item room, treasure room, item room poolgrey, gray, Allows you to fire a red flame infront of you, similar to the Blue Candle item, however the flame will stay 10 seconds, Each flame deals 125 total damage before it disappears, The flame will shrink in size when deals damage to something and eventually disappear, REPENTANCE - Red Candle flames now time out after ten seconds and automatically extinguish. A blood clot is a bodily process that prevents excessive bleeding by forming a clot where the immense blood flow is, but can be harmful if it blocks an important passageway to a body organ. The chance for a Red Room to unlock increases as you pick up more Crystal Keys. Even though they look like reskins of Cain, Isaac, Lilith, and the rest, most of them start with new items and abilities, effectively doubling the way you can begin a new run once they're unlocked. Blood Donation machines, UNLOCK: Unlock this item by beating the Isaac boss with The Lost, * item room, treasure room, item room pool, red, isaacs heart, A familiar ghost that follows Isaac around and chases enemies close-by, damaging them for 2 contact damage and causing a fear effect, * item room, treasure room, item room pool, white, lil' haunt, A familiar beggar similar to Bum Friend that follows Isaac and collects red hearts, giving Isaac black hearts, pills, cards, runes or spiders in return, For every 1.5 red hearts he takes, he will give a reward, Reward chances: Black Heart - 40%, Card/Rune - 20%, Pill - 20%, Blue Spider - 10%, Spider 10%, Item Pool: Item Room, Devil Room, Demon Beggar, * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, celebrate good times come on, the lost item pool, qt 3.14, dark bum, otp, damn it reddit, horns, grey, gray, smile, A very large orbital that moves around Isaac very slowly, blocking shots and dealing 2 contact damage per tick, Affects the speed of all other orbitals, slowing them down a lot (NOTE: This effect does not happen until you get a new orbital after Big Fan), Does not count as one of your three standard orbital slots, * item room, treasure room, item room pool, fat, brown, An adorable friendly blue spider that walks around the room laying other blue spiders which attack enemies, She can only spawn a maximum of up to 5 spiders at a time and will only do so while there are enemies in the room, REPENTANCE - Sissy Longlegs now charms enemies upon contact, * item room, treasure room, sissy longlegs item room pool, qt 3.14, dark bum, otp, damn it reddit, blue, derpface, Spawns a friendly Mulligan that walks around the room. PC 9SS3 3YXY (Second floor treasure room) (+ Technology 2 on third floor), PC GXSE V7P4 (Treasure Room adjacent to spawn), PC EZTZ CL68 (Treasure Room adjacent to spawn), PC RR0G KKQJ (Treasure Room adjacent to spawn), PC 6FDS 6FWF (Treasure Room adjacent to spawn), PC PCM8 R3H4 (Treasure Room adjacent to spawn), PS4 GXA1 L6XC (Treasure Room adjacent to spawn), PS4 27T2 26G0 (First floor Treasure Room), 3DS 11DA E0JZ (Treasure Room adjacent to spawn), Switch AL2T Q6NC (First Golden Treasure Room), Achievements Multi-shot effects add 1 bomb to the barrage, up to 21 bombs. uses as his main mechanic, Killing or damaging enemies spawns various poops, which add to his collection. Items Taking this item DOES count as a devil deal, preventing future angel rooms. Counts as 1 of 3 mushroom items needed towards the Fun Guy transformation. The item called Zodiac does not count. No longer drops black hearts like it used to. The 2 permanent stat increases depend on the item taken: A Snack = +0.2 shot speed, +1 luck. Isaac appears demonic with large curved horns and an angry expression. The finger deals 10% of your normal damage to all enemies in the same direction that the finger is pointing, The finger will also deal damage to entities such as fires and poops, Applies on-hit status effects such as the burning debuff from Fire Mind, Spawns guppy flies if you have the Guppy transformation, Isaac gains a shadow familiar that will follow Isaac's movement pattern delayed by 1 second and deal 5 contact damage to enemies per tick, Shade is absorbed by Isaac after dealing 666 damage. ?, Satan and The Lamb as Tainted Eve, A small clot friend will hug Isaac, following his exact movements (similar to how Jacob & Esau work) and shooting tears when he does, The clot can be moved around by collision with an object/wall, allowing you to re-position it, The clot's damage is roughly 1/3 of your tear damage, If it takes a few hits it will die, and respawn in the next room, UNLOCK: Unlock this trinket by defeating Mother as Tainted Eve, Spawns a random chest after completing a regular Challenge Room, Spawns a pedestal item after completing a boss Challenge Room, UNLOCK: Unlock this trinket by defeating Isaac, ?? Character Appearance Guarantees a Planetarium if an item room has been skipped, otherwise +15% chance for Planetariums to spawn while held. It also changes tears to a chargeable laser that pierces all objects in its path (including enemies, environmental hazards and walls). Blood clots can have d. These damage increases do not stack with each other. The Forgotten - Your Soul is now unchained and free to move. Based on the Steam Workshop mod created by Niro, A familiar with a charged attack, that spawns a line of creep on the floor which damages enemies that walk over it, The familiar and its creep will change randomly when Isaac uses a pill, Possible creep types include green (deals damage), black (slows enemies), red (deals damage, forms a line with a larger puddle), yellow (deals damage, forms a short-range cone) and white (slows enemies, forms a ring), Added as part of the Afterbirth+ Booster Pack #5. Can only happen once per room, Visually this is almost identical to the Guardian Angel item, but without a face, UNLOCK: Unlock this item by beating Blue Womb (Hush) with The Lost, A white orbiting fly which deals 3 contact damage per tick to enemies, This familiar orbits Isaac at a middle length distance somewhere between Distant Admiration and Forever Alone, Item Pool: Item Room, Greed Mode Item Room, Key Beggar. The longer the button is held the faster Gurdy will fling itself across the screen, Deals a fixed amount of damage depending on charge level, at lowest being ~5 and at max being ~20, Lil Gurdy bounces off of enemies and obstacles, A beggar head which floats around the room and picks up any nearby coins. * shop room pool, shop item pool, the lost item pool, white, Causes Isaac's head to detach and orbit his body, blocking shots and dealing 7 contact damage per tick, BFFs will cause the Guillotine head to do double damage (14 damage per tick), Tears are still fired from Isaac's head but the hitbox remains around his body, UNLOCK: Unlock this item by beating the Isaac boss with Judas, * item room, treasure room, item room pool, chop, head, silver, metal, Gives Isaac an orbital ball of bandages that deals 7 contact damage per tick and blocks enemy shots, Collecting a second Ball of Bandages in the run turns the orbital into a pink head that shoots tears that deal 7 damage each and have a chance to charm enemies, Getting a third Ball of Bandages will transform the head into bandage girl which will chase enemies dealing 3.5 contact damage per tick while firing charm tears, A fourth Ball of Bandages will make the Bandage Girl bigger and stronger, making her deal 5.5 damage per tick instead, Any further Ball of Bandages will repeat the cycle, Increases the chance of champion enemies appearing by 15%, Doesn't affect the chance for champion bosses to spawn, * shop room pool, shop item pool, red, croissant, crescent, Bombs now become poop bombs, which deal 10 damage to all enemies in the room and daze them for a short period of time, Butt Bombs heal the poop bosses (Dingle, Dangle, Brownie) by 25% of their max HP, * boss rush pool, boss rush room, item room, treasure room, item room pool, poop, face, brown, If Isaac stands still and stops shooting for a second, he turns to stone, making him invincible until he moves/shoots again, Using bombs or your active item will remove the invicibility as well, This item is a reference to the Tanuki suit in Super Mario 3, * item room, treasure room, item room pool, raccoon, green, Spawns 2-5 friendly attack spiders every time you take damage, REPENTANCE - Buffed, used to spawn 1-2 spiders, * item room, treasure room, item room pool, the lost item pool, purple, blue, heart, cute spider baby, When Isaac dies, he has a 50% chance to resurrect with 1/2 a heart, * curse room pool, red chest pool, red chest item pool, devil pool, devil room pool, devil deal, If Brimsnap is used and it coincides with. Butt Bombs, Hot Bombs), When used will teleport you to another random room that has not been explored yet, After all the normal rooms have been explored, the hierarchy of rooms chosen is: Boss Room, Super Secret Room, Shop, Item Room, Sacrifice Room, Dice Room, Library, Curse Room, Miniboss, Challenge Room, Bedroom, Arcade, Vault, Secret Room, Devil/Angel Room, I AM ERROR, This ordering means a Devil and I Am Error room can both be forced if all others have been visited, If used in a normal room with enemies it will teleport you out and back into the exact same room, *, golden, yellow, robot, antenna, black, teleport two, teleport 20, Walking in a circle will spawn a pentagram symbol on the floor, which deals 10 damage per tick to any enemies inside it, The trail of black powder left on the floor will quickly disappear, meaning you are limited on the size of the pentagram symbol you can create, REPENTANCE - Black Powder's pentagram can now damage flying enemies, When used, applies the charm effect to any enemies in close range and deals 5 damage. Based on the Steam Workshop mod created by by Scayze and Ashkait, *, bloody, paper, script, white, red, toilet paper, seven seals. the ability to fly. 3c pickups become 2c, Taking more than 1 steam sale reduces the price of all items even further, This item is called Steamy Sale on PS4, PS Vita, Xbox One and Switch versions, probably due to copyright reasons, Item Pool: Shop, Greed Miniboss, Shopkeeper, * shop room pool, shop item pool, red, pink, white, paper, Spawns 6 troll bombs at random locations around the room, Bombs are effected by other passive bomb items, Has a chance to drop from the Pride miniboss fight, Item Pool: Item Room, Library, Pride Miniboss, * Anarchist's Cookbook, Anarchists Cookbook library pool, library room, book room pool, item room, treasure room, item room pool, UNLOCK: Unlock this item by defeating Delirium as Azazel, *, red, glow, Dark Prince's Crown, dark princes crown, dark prince crown, Gives you a 6.66% chance to fire a razor blade which deals x4 damage, This item also turns your tears red, but does not change your actual damage stat or the damage your normal tears do, The chance to fire a razor blade depends on your luck stat, and at +14 luck you will fire a razor blade every time, With every 15 tears fired, Isaac will fire a cluster of 12 tears instead of your normal tear, Causes your normal tears to fire out of one eye, which means tears will fire in a near-perfect line instead of slightly off-center, REPENTANCE - Lead Pencil's tear barrage no longer deals double damage, When entering a room connected to a Secret Room or Super Secret Room, a howling sound will play, When entering a room with a crawl space trapdoor in it, a barking sound will play, While firing, you gain a green aura that poisons any enemies which touch it. 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