This site uses cookies. MCC hat an AdBoards von Ipsen und Novartis teilgenommen sowie Reisekosten und Kongressbesuche von Ipsen und Novartis erhalten. In such cases, treatment with dopamine agonists can be resumed. 2010;162:453–475. Bull. Docosahexaenoic acid inhibits mechanical allodynia and thermal hyperalgesia in diabetic rats by decreasing the excitability of DRG neurons. Development of a Model for Predicting the Effectiveness of Pulsed Radiofrequency on Zoster-Associated Pain. government site. 9 Medicover Neuroendokrinologie, München, Germany. Psychol Med 10: 35–53, Desir D, Cauter E van, Fang VS et al. Brief Summary: A Phase 2 double-blind, placebo-controlled, randomized withdrawal study is designed to evaluate the safety, efficacy, and pharmacokinetics of paltusotine (formerly CRN00808; an oral selective nonpeptide somatostatin receptor type 2 biased agonist) in subjects with acromegaly that are responders to octreotide LAR or lanreotide depot. Arch Gen Psychiatry 42: 909–914, Hellman L, Nakada F, Curti J et al. An official website of the United States government. Accessibility Diabetes Care 41 1068–1075. Accessibility Epub 2022 Jan 30. (1986) Human corticotropin-releasing factor induced modulation of sleep architecture and hormone secretion — Comparison with basal sleep endocrine studies in male controls and patients with depression or sexual dysfunction. Total score computed by adding each of the individual acromegaly symptom intensities (headache pain, joint pain, sweating, fatigue, weakness in legs, swelling, numbness or tingling). In DPN patients, DRG volume was negatively correlated with the neuropathy disability score (r = -0.43; 95%CI = -0.66 to -0.14; p = 0.02), a measure of neuropathy severity. Change from baseline in serum phosphate will be evaluated. J. Gen. Intern. ∗p-value < 0.05; ∗∗p, Group comparison between participants with and without progression for albuminuria for DNA damage measured by comet tail length (median in % with 95% CI) and ɤH2AX-positivity (Frequent of the parent in % with 95% CI) (A and B); for senescence measured by urinary p21-positivity (pg/ml; log-transformed with 95% CI) (C) and for senescence-associated secretory phenotype (measured by IL6 and TGF-β1 (both in pg/ml with 95% CI) (D and E). Haploinsufficiency of Tmem43 in cardiac myocytes activates the DNA damage response pathway leading to a late-onset senescence-associated pro-fibrotic cardiomyopathy. Epub 2015 Nov 14. -. Magnetic resonance neurography detects diabetic neuropathy early and with Proximal Predominance. The site is secure.
Relation to a possible central nervous system etiology. Psychiatry Res 17: 49–59, Matussek N, Ackenheil M, Hippius H, Müller F, Schroder H-T, Schultes H, Wasilewski B (1980) Effect of clonidine on growth hormone release in psychiatric patients and controls. AL hat Honorare von Ipsen, Pfizer, Novartis, Merck, Eli Lilly, Sandoz und Novo Nordisk für Vorträge und/oder Beratungstätigkeit erhalten. His clinical focus areas are endocrinology, neuroendocrinology, diabetology and andrology. Google Scholar, Jarrett DB, Coble PA, Kupfer DJ (1983) Reduced cortisol latency in depressive illness. 8600 Rockville Pike Please enable it to take advantage of the complete set of features! This site needs JavaScript to work properly. Accessibility -, Andersen S. T., Witte D. R., Dalsgaard E.-M., Andersen H., Nawroth P., Fleming T., et al. Study Design Go to 2022 Nov 2;12(11):2669. doi: 10.3390/diagnostics12112669. MD hat Honorare für Vorträge und/oder Beratertätigkeit von Ipsen, Pfizer, Novartis, Sandoz und Shire erhalten. Procedures, variations in total plasma proteins and disruption of adrenocorticotropincortisol periodicity. . official website and that any information you provide is encrypted Management of prolactinomas: a survey of physicians from the Middle East and North Africa. Background: Gittoes N, Rejnmark L, Ing SW, Brandi ML, Bjornsdottir S, Hahner S, Hofbauer LC, Houillier P, Khan AA, Levine MA, Mannstadt M, Shoback DM, Vokes TJ, Zhang P, Marelli C, Germak J, Clarke BL. Troponin T Is Negatively Associated With 3 Tesla Magnetic Resonance Peripheral Nerve Perfusion in Type 2 Diabetes. Unauthorized use of these marks is strictly prohibited. 2018 Bibliography , Sie können den eintreffenden Notärzten oder Rettungsassistenten gegebenenfalls auch eine von Ihnen bevorzugte Notfallklinik nennen. MCC participated in AdBoards of Ipsen and Novartis and received travel expenses and expenses for conferences from Ipsen and Novartis. Vorschlag zur Therapie des Prolaktinoms während der Schwangerschaft, modifiziert nach , , . To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Incidence rate of the renal events will be recorded for nephrolithiasis, nephrocalcinosis, hospitalization/emergency room visits for renal events. (Clinical Trial), An Open Label Exploratory Study to Evaluate the Safety, Pharmacokinetics and Efficacy of CRN00808 in Patients With Acromegaly Treated With Somatostatin Analogue Based Treatment Regimens (ACROBAT Edge), 18 Years to 70 Years (Adult, Older Adult), Keck Medical Center of USC University of Southern California, Los Angeles, California, United States, 90033, Los Angeles, California, United States, 90095, Northwestern University Feinberg School of Medicine, Baltimore, Maryland, United States, 21287, Boston, Massachusetts, United States, 02114, Ann Arbor, Michigan, United States, 48106, Pittsburgh, Pennsylvania, United States, 15212, CETI - Centro de Estudos em Terapias Inovadoras, Hospital Universitário Clementino Fraga Filho (HUCFF/UFRJ) Centro de Pesquisa em Neuroendocrinologia, General Hospital of Athens "Evangelismos", Military Health Center, Division of Endocrinology, Semmelweis University Faculty of Medicine, Azienda Ospedaliera Universitaria Federico II, Waitemata District Health Board, North Shore Hospital, Endocrine, Diabetes and Research Centre, Wellington Hospital, Clinic of Endocrinology Independent Public Health Care Centre University Hospital in Kracow, Centrum Nowoczesnch Terapii "Dobry Lekarz", The Centre of Postgraduate Medical Education, National Institute of Endocrinology "C. I. Parhon", Emergency Clinical County Hospital, Endocrinology Clinic, Clinical Centre Serbia, Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Centre of Vojvodina, Clinic for Endocrinology, Diabetes and Metabolic Diseases, National Institute of Endocrinology and Diabetology, University Hospitals Coventry and Warwickshire NHS Trust. But this will always prompt you to accept/refuse cookies when revisiting our site. Some of the focuses of treatment of Professor Stalla are: Obesity Pituitary diseases Pharmacological characterization of different fractions of Calotropis procera (Asclepiadaceae) in streptozotocin induced experimental model of diabetic neuropathy. 8600 Rockville Pike National Library of Medicine Eur J Endocrinol. IKA and SP received honoraria for lectures and/or consultancy work as well as travel costs from Ipsen, Novartis and Pfizer. JF hat an AdBoards von Ipsen, Novartis und Bristol-Myers Squibb teilgenommen. Bethesda, MD 20894, Web Policies Pituitary surgery within 6 months prior to Screening or radiation therapy at any time prior to the study entry. Arch Gen Psychiatry 39: 189–192, Halbreich U, Asnis GM, Shindledecker R, Zumoff B, Nathan RS (1985) Cortisol secretion in endogenous depression. Neuroendokrinologie und Schlaf. Choosing to participate in a study is an important personal decision. Netzwerk Neuroendokrine Tumoren (NeT) e. V. ERN-EURACAN European Reference Network for rare adult solid cancers, Bayerisches Krebsregister - Informationen für Patientinnen und Patienten. Read our, ClinicalTrials.gov Identifier: NCT01922440, Observational
eCollection 2023. History of hypoparathyroidism resulting from impaired responsiveness to PTH (pseudohypoparathyroidism). Magnetic Resonance Neurography Reveals Smoking-Associated Decrease in Sciatic Nerve Structural Integrity in Type 2 Diabetes. sharing sensitive information, make sure you’re on a federal We need 2 cookies to store this setting. and transmitted securely. Pain Ther. Springer, Berlin, Heidelberg. J Clin Endocrinol 26: 1173. Management of prolactinomas during pregnancy. J Endocrinol. -, Al-Aubaidy H.A., Jelinek H.F. Oxidative DNA damage and obesity in type 2 diabetes mellitus. Epub 2018 Mar 10. 2011;164(6):899–904. Change from baseline in serum magnesium will be evaluated. Pham M, Oikonomou D, Hornung B, Weiler M, Heiland S, Bäumer P, Kollmer J, Nawroth PP, Bendszus M. Ann Neurol. government site. Methods: Kidney, lung, and liver were studied in 4 months diabetic db/db mice and age-matched controls for the presence of DNA damage . J. Biol. 17 483–489. Epub 2018 Apr 25. Zusammenfassung. -, Clair C., Cohen M. J., Eichler F., Selby K. J., Rigotti N. A. J Clin Endocrinal Metab 52: 628, CrossRef 10.2337/dc17-2062 Her primary research focus is. Recommendations on the treatment of prolactinoma in pregnancy, modified from Am J Psychiatry 140: 750–753, Carlson HE, Gillin JC, Gorden P, Snyder F (1972) Absence of sleep-related growth hormone peaks in aged normal subjects and in acromegaly. Selbsthilfegruppen, Initiativen, Beratung, Comprehensive Cancer Center München (CCC München). Bookshelf 2022 May 10;13:839774. doi: 10.3389/fendo.2022.839774. National Library of Medicine Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03789656, The new site is coming soon - go to the modernized. Clipboard, Search History, and several other advanced features are temporarily unavailable. The https:// ensures that you are connecting to the This global registry is expected to enroll a minimum of 900 participants, of whom at least 300 will be participants treated with rhPTH(1-84) and at least 600 will be participants receiving standard of care. See this image and copyright information in PMC. April 2012 - September 2017. Change from baseline in 25-OH vitamin D will be evaluated. (1973) Temporal patterns of integrated plasma hormone levels during sleep and wakefulness. Herzlich willkommen im Zentrum für Neuroendokrine Tumoren des Gastroenteropankreatischen Systems am CCC Münchenᴸᴹᵁ - GEPNET Das GEPNET-KUM ist eines der Zentren des Comprehensive Cancer Center CCC München LMU und von der European Neuroendocrine Tumor Society (ENETS) zertifiziertes Center of Excellence. JS hat Honorare für Vorträge und Beratertätigkeiten sowie Reisekosten von Ipsen, Novartis und Pfizer erhalten und an Studien von Ipsen, Novartis, Pfizer und Chiasma teilgenommen. An official website of the United States government. 2022 Mar 31;13:869414. doi: 10.3389/fendo.2022.869414. An SAE is any untoward medical occurrence (whether considered to be related to study product or not) that at any dose results in death, life-threatening, requires inpatient hospitalization or prolongation of existing hospitalization, results in persistent or significant disability/incapacity, is a congenital abnormality or birth defect, an important medical event. Front Endocrinol (Lausanne). Biologische Psychiatrie. Incidence rate of the soft tissue calcifications (site) will be recorded. 30 1193–1203. Federal government websites often end in .gov or .mil. BMC Endocr Disord. The progression of nephropathy over 4 years was predicted by increased DNA damage, senescence, and SASP, while the progression of RLD was associated with increased DNA damage and IL-6 only. Keywords: and transmitted securely. At the MEDICOVER Neuroendocrinology in Munich Professor Stalla works as an internal medicine doctor, endocrinologist and andrologist. https://doi.org/10.1007/978-3-642-72923-2_15, Tax calculation will be finalised during checkout. 2017;27:315–389. 2021 Nov 25;12:765201. doi: 10.3389/fendo.2021.765201. Neuropsychobiology 1: 70–79, Sherman B, Wysham C, Pfohl B (1985) Age-related changes in the circadian rhythm of plasma cortisol in man. Deletion of Smad3 prevents renal fibrosis and inflammation in type 2 diabetic nephropathy. National Library of Medicine Unauthorized use of these marks is strictly prohibited. db/db mice showed an increased nuclear ɤH2AX signal in all tissues as compared to the background control. Incidence rate of the bone fractures (site) will be recorded. Adresse: Orleansplatz 3, 81667 München. Beshyah SA, Sherif IH, Chentli F, Hamrahian A, Khalil AB, Raef H, El-Fikki M, Jambart S. Pituitary. Methods: National Library of Medicine Biol Psychiatry 19: 1537–1550, Krieger DT, Glick SM (1972) Growth hormone and cortisol responsiveness in Cushing’s syndrome. In vivo imaging of dorsal root ganglia (DRG), a key structure for the understanding of DPN, has been restricted to animal studies. 2020 Feb;294(2):405-414. doi: 10.1148/radiol.2019191347. These have shown a correlation of decreased DRG volume with neuropathic symptom severity. Garmes HM, Boguszewski CL, Miranda PAC, Martins MRA, da Silva SRC, Abucham JZ Filho, de Castro Musolino NR, Vilar L, Portari LHC, Gadelha MR, Kasuki L, Naves LA, Czepielewski MA, de Almeida TS, Duarte FHG, Glezer A, Bronstein MD. 2022 Aug 13;58(8):1095. doi: 10.3390/medicina58081095. Orv Hetil. Participants will be treated according to their clinic's standard practice determined by the treating doctors. Da sowohl die Schlafarchitektur, wie auch die endokrine Aktivität bei Patienten mit affektiven Erkrankungen charakteristisch verändert sind, haben Untersuchungen zur Schlafendokrinologie in den letzten Jahren besonderes Interesse gefunden (Steiger et al. Human dorsal root ganglia (DRG) segmentation. Herzlich willkommen! . (A) Left and right L5 dorsal root…, L5 dorsal root ganglion (DRG) volume and normalized signal intensity (SI) versus neuropathy…, MeSH Change from baseline in serum albumin will be evaluated. The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response. Google Scholar, Finkelstein JW, Roffwarg HP, Boyar RM, Kream J, Hellman L (1972) Age-related change in the twenty-four-hour spontaneous secretion of growth hormone. Participants who had been treated with rhPTH(1-34) within 3 months of enrollment are also excluded as are participants currently using rhPTH(1-34). The rate of hospitalizations and ER visits during follow-up will be summarized. Gabra BH, Berthiaume N, Sirois P, Nantel F, Battistini B. Biol Chem. PubMed . RF hat Reisekosten und Kongressbesuche finanziert bzw. dem Patienten zugute kommen sollen. J Clin Endocrinol Metab. PMID: 33100960 PMCID: PMC7546893 DOI: 10.3389/fnins.2020.570744 Abstract Diabetic neuropathy (DPN) is one of the most severe and yet most poorly understood complications of diabetes mellitus. Disclaimer. PMC Bookshelf PubMed Google Scholar, Psychiatrischen Klinik und Poliklinik, Univresität München, Nußbaumstraße 7, D-8000, München 2, Deutschland, Prof. Dr. Hanns Hippius (Direktor) & Dr. Max Schmauss (Oberarzt) (Direktor) & (Oberarzt), Psychiatrischen Klinik, Universität Göttingen, v.-Siebold-Straße 5, D-3400, Göttingen, Deutschland, Prof. Dr. Eckart Rüther (Direktor) (Direktor), Steiger, A., Holsboer, F. (1988). Measurement and reliability: statistical thinking considerations. 11. Each participant will fill out a study questionnaire during a routine doctor visit. MD received honoraria for lectures and/or consultancy work from Ipsen, Pfizer, Novartis, Sandoz and Shire. View this study on Beta.ClinicalTrials.gov, Genetic and Rare Diseases Information Center, U.S. Department of Health and Human Services, The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. sharing sensitive information, make sure you’re on a federal See this image and copyright information in PMC. Pituitary surgery within 6 months prior to Screening. Auf Grund unserer Erfahrung und unseres Wissens bieten wir die Diagnostik und Therapie nicht nur einzelner, sondern aller . Individual Participant Data (IPD) Sharing Statement: Studies a U.S. FDA-regulated Drug Product: Studies a U.S. FDA-regulated Device Product: Change from baseline (mean of Screening values) in insulin-like growth factor-1 (IGF-1) level [ Time Frame: 13 Weeks ], Proportion of subjects with their last IGF-1 measurement ≤ upper limit of normal (ULN) [ Time Frame: 13 Weeks ], Proportion of subjects with their last IGF-1 measurements ≤1.5×ULN [ Time Frame: 13 Weeks ], Male and female subjects 18 to 70 years of age, Confirmed diagnosis of acromegaly with either a partial or complete response to protocol defined somatostatin analogue therapy regimens, Females must be non-pregnant and non-lactating, and either surgically sterile, post-menopausal, or using effective method(s) of birth control, Willing to provide signed informed consent. HHS Vulnerability Disclosure, Help Before (Clinical Trial), Triple (Participant, Care Provider, Investigator), A Double-blind, Placebo-controlled, Randomized Withdrawal Study to Evaluate the Safety, Pharmacokinetics and Efficacy of CRN00808 in Patients With Acromegaly That Are Responders to Octreotide LAR or Lanreotide Depot (ACROBAT Evolve), 18 Years to 70 Years (Adult, Older Adult), Keck Medical Center of USC University of Southern California, Los Angeles, California, United States, 90033, Los Angeles, California, United States, 90095, Northwestern University Feinberg School of Medicine, Baltimore, Maryland, United States, 21287, Boston, Massachusetts, United States, 02114, Ann Arbor, Michigan, United States, 48106, Pittsburgh, Pennsylvania, United States, 15212, CETI - Centro de Estudos em Terapias Inovadoras, Hospital Universitário Clementino Fraga Filho (HUCFF/UFRJ) Centro de Pesquisa em Neuroendocrinologia, General Hospital of Athens "Evangelismos", Military Health Center, Division of Endocrinology, Semmelweis University Faculty of Medicine, Azienda Ospedaliera Universitaria Federico II, Waitemata District Health Board, North Shore Hospital, Endocrine, Diabetes and Research Centre, Wellington Hospital, Clinic of Endocrinology Independent Public Health Care Centre University Hospital in Kracow, Centrum Nowoczesnch Terapii "Dobry Lekarz", The Centre of Postgraduate Medical Education, National Institute of Endocrinology "C. I. Parhon", Emergency Clinical County Hospital, Endocrinology Clinic, Clinical Centre Serbia, Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Centre of Vojvodina, Clinic for Endocrinology, Diabetes and Metabolic Diseases, National Institute of Endocrinology and Diabetology, University Hospitals Coventry and Warwickshire NHS Trust. Thyroid hormone ameliorates diabetic nephropathy in a mouse model of type II diabetes. -, Melmed S, Casanueva F F, Hoffman A R. Diagnosis and treatment of hyperprolactinemia: an Endocrine Society clinical practice guideline. (1983) Plasma cortisol secretion and REM period latency in adult endogenous depression. GS received honoraria for lectures and/or consultancy work and travel costs from Ipsen, Novartis, Novo Nordisk, Pfizer, Sandoz and Shire. Psychiatry Res 10: 191–199, Kupfer DJ, Reynolds CF III, Grochocinski VJ, Ulrich RF, McEachran A (1986) Aspects of short REM latency in affective states: A revisit. Management of hypopituitarism: a perspective from the Brazilian Society of Endocrinology and Metabolism. Med. Umgekehrt ist die Phase der schlafassoziierten Höchstsekretion von Wachstumshormon zeitlich eng an den Schlafbeginn gebunden. J Clin Endocrinol Metab 34: 1102–1105, Checkley SA (1980) Neuroendocrine tests of monoamine function in man: A review of basic theory and its application to the study of depressive illness. 2022 Feb 15;15:811085. doi: 10.3389/fnins.2021.811085. Pituitary radiation therapy (within 3 to 4 years or more than 4 years prior to study entry) with recently documented elevated IGF-1 may be eligible. If the primary tumor is large and the risk that it will continue to grow is high, it may be necessary to continue medical treatment from the start of pregnancy. Subjects receiving radiation therapy may be eligible with some restrictions. Subjects with clinically significant abnormal findings during the Screening Period, and any other medical condition(s) or laboratory findings that, in the opinion of the Investigator, might jeopardize the subject's safety or ability to complete the study, Subjects who have been taking the following prior medications: pegvisomant (within the last 3 months), dopamine agonists (within the last 3 months) and pasireotide LAR (within the last 6 months), Subjects taking octreotide LAR at a dose higher than 40 mg or lanreotide depot at a dose higher than 120 mg, Subjects who usually take octreotide LAR or lanreotide depot less frequently than every 4 weeks (e.g. Overall, 55 diabetes patients (66 ± 9 years; 32 men; 30 with DPN) took part in this study. sharing sensitive information, make sure you’re on a federal 2009 Sep 27;150(39):1803-10. doi: 10.1556/OH.2009.28584. We also use different external services like Google Webfonts, Google Maps, and external Video providers. In patients with diabetes, the progression of complications in the kidney and lung is predicted by markers reflecting DNA damage, and senescence-triggered organ fibrosis. Medicover Neuroendokrinologie, München, Germany Key words pituitary disease, pituitary tumor, pregnancy, fertility,diabetes insipidus Schlüsselwörter Hypophysenerkrankungen, Hypophysentumor,Schwangerschaft, Fertilität, Diabetes insipidus received revised accepted 9. Findings: By continuing to browse the site, you are agreeing to our use of cookies. Information provided by (Responsible Party): A Phase 2 double-blind, placebo-controlled, randomized withdrawal study is designed to evaluate the safety, efficacy, and pharmacokinetics of paltusotine (formerly CRN00808; an oral selective nonpeptide somatostatin receptor type 2 biased agonist) in subjects with acromegaly that are responders to octreotide LAR or lanreotide depot. You can also change some of your preferences. J Gerontol 38: 519–524, Quabbe H-J, Schilling E, Helge H (1966) Pattern of growth hormone secretion during a 24-hour fast in normal adults. Bethesda, MD 20894, Web Policies View this study on Beta.ClinicalTrials.gov, Genetic and Rare Diseases Information Center, U.S. Department of Health and Human Services, The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. HHS Vulnerability Disclosure, Help (1974) Effects of a prolonged 3-hour sleep-wake cycle on sleep stages, plasma cortisol, growth hormone and body temperature in man. Minerva Endocrinol. Minerva Endocrinol. Diese sind der Campus Innenstadt und der Campus Großhadern. You are free to opt out any time or opt in for other cookies to get a better experience. -, Chakraborty S., Karmakar K., Chakravortty D. Cells producing their own nemesis: understanding methylglyoxal metabolism. In this cross-sectional study, participants underwent 3T MRN of both L5 DRG using an isotropic 3D T2-weighted, fat-suppressed sequence with subsequent segmentation of DRG volume and analysis of normalized signal properties. This work was supported by the German Research Foundation (DFG) in the CRC 1118 and CRC 1158, by the GRK DIAMICOM, by the German Center for Diabetes Research (DZD e.V. You can check these in your browser security settings. Cellular Senescence in Diabetes Mellitus: Distinct Senotherapeutic Strategies for Adipose Tissue and Pancreatic β Cells. (1970) Cortisol is secreted episodically by normal man. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. We may request cookies to be set on your device. Xu BH, Sheng J, You YK, Huang XR, Ma RCW, Wang Q, Lan HY. Orleansplatz 3 81667 München Tel: +49 89 9042005-60 Fax: +49 89 9042005-61 neuroendo@medicover.de Sprechzeiten Termin online vereinbaren Termin online vereinbaren Unser digitaler Telefonassistent - jederzeit für Sie im Einsatz Ihr Anliegen wollen wir jederzeit schnell und sicher entgegennehmen. 2011;96:273–288. Der Schlaf ist nicht nur durch eine erhebliche physiologische Aktivität gekennzeichnet, sondern auch durch charakteristische Sekretionsmuster von Kortisol und Wachstumshormon. J Clin Endocrinol Metab 60: 505–512, Pfohl B, Sherman B, Schlechte J, Stone R (1985) Pituitary-adrenal axis rhythm disturbances in psychiatric depression. Arch Gen Psychiatry 32: 31, Halbreich U, Sachar EJ, Asnis GM, Quitkin F, Nathan RS, Halpern F, Klein DF (1982) Growth hormone response to dextroamphetamine in depressed patients and normal subjects. I. Thyroid-stimulating hormone, growth hormone and cortisol. Metabolism. The most well-established forms of treatment are for prolactinoma, due to the incidence of this disease and its impact on fertility. Field of study. Popescu AD, Carsote M, Valea A, Nicola AG, Dascălu IT, Tircă T, Abdul-Razzak J, Țuculină MJ. Would you like email updates of new search results? A Phase 1b Study in Patients With Acromegaly or Functioning Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs) to Characterize the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Debio 4126, a 12-week Prolonged-release Octreotide Formulation The site is secure. Health, Washington D.C. Rubin RT, Gouin PR, Areander AT, Poland RE (1973) Human growth hormone release during sleep following prolonged flurazepam administration.